Addition of pearl barley to a rice-based diet for newly weaned piglets increases the viscosity of the intestinal contents, reduces starch digestibility and exacerbates post-weaning colibacillosis
Addition of pearl barley to a rice-based diet for newly weaned piglets increases the viscosity of the intestinal contents, reduces starch digestibility and exacerbates post-weaning colibacillosis
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DOI：
10.1079/bjn20041206
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发表时间：
2004-09-01
影响因子：
3.6
通讯作者：
Hampson, DJ
中科院分区：
文献类型：
--
作者：
Hopwood, DE;Pethick, DW;Hampson, DJ
本研究的目的是调查饲喂含有NSP的谷物对最近断奶的猪的身体生长和肠道微环境的影响，并检查由此产生的与肠道中致病性大肠杆菌的关联。试验1中，将富含可溶性NSP的谷物--珍珠大麦（250、500或750 g/kg日粮）添加到以熟白色大米为基础的低纤维对照日粮中，并在断奶后饲喂7-10 d。与对照组相比，薏米对仔猪增重无显著影响，但可促进大肠生长和发酵，降低回肠淀粉消化率，增加肠道粘度。实验2是为了确定这些差异是否有利于产肠毒素E.大肠杆菌，引起断奶后大肠杆菌病（PWC）的细菌。将三组猪断奶至基于煮过的白色大米、含有500克珍珠大麦/千克的大米或含有500克珍珠大麦/千克的大米并补充外源酶（Porzyme TM 100; Danisco，马尔伯勒，Wilts.，英国）。猪经口接种溶血性E.大肠杆菌血清型O 8、K87、K88。食用珍珠大麦的动物肠道内容物的粘度增加，大肠杆菌在肠道的定植增加。大肠杆菌菌株和更多的腹泻比只喂大米的饮食。酶不降低粘度或防止PWC。结果表明，珍珠大麦改变肠道微环境，易患PWC，而低粘度，高消化率的饮食的基础上煮熟的白色大米是保护。
The purposes of the present study were to investigate the effects of feeding a cereal grain containing NSP on body growth and the intestinal microenvironment of recently weaned pigs, and to examine resultant associations with pathogenic Escherichia coli in the intestinal tract. In Expt 1, pearl barley, a grain rich in soluble NSP, was incorporated (250, 500 or 750 g/kg diet) into a low-fibre control diet based on cooked white rice and fed for 7-10 d following weaning. Consumption of pearl barley did not significantly alter piglet live-weight gain compared with the control cooked rice diet, but it accelerated large intestinal growth and fermentation, decreased ileal starch digestibility and increased intestinal viscosity. Expt 2 was conducted to determine whether these differences would favour proliferation of enterotoxigenic E. coli, the bacterium causing post-weaning colibacillosis (PWC). Three groups of pigs were weaned onto diets based on cooked white rice, rice with 500 pearl barley/kg, or rice with 500 g pearl barley/kg supplemented with exogenous enzymes (Porzyme(TM) 100; Danisco, Marlborough, Wilts., UK). Pigs were inoculated orally with haemolytic E. coli serovar O8;K87;K88 after weaning. Animals eating the pearl barley had increased viscosity of the intestinal contents, greater intestinal colonisation with the E. coli strain and more diarrhoea than pigs fed the rice-only diet. The enzymes did not reduce viscosity or protect from PWC. The results suggest that pearl barley alters the intestinal microenvironment and predisposes to PWC, whilst a low-viscosity, highly digestible diet based on cooked white rice is protective.