ISOLATION OF CB-25-I, AN ANTIFUNGAL ANTIBIOTIC, FROM SERRATIA-PLYMUTHICA
ISOLATION OF CB-25-I, AN ANTIFUNGAL ANTIBIOTIC, FROM SERRATIA-PLYMUTHICA
复制标题
DOI：
10.7164/antibiotics.42.869
复制
发表时间：
1989-06-01
影响因子：
3.3
通讯作者：
TERUI, Y
中科院分区：
文献类型：
--
作者：
SHOJI, J;HINOO, H;TERUI, Y
从普城沙雷氏菌菌株的培养液中分离出一种新的抗真菌抗生素 CB-25-I。这种抗生素是一种水溶性二肽，在结构上与 Sch 37137 和 A 19009 相关，两者均由放线菌菌株产生。该抗生素在 YNB 培养基（一种合成培养基）中表现出对白色念珠菌的抑制活性，但在沙氏葡萄糖培养基中活性显着降低。
A new antifungal antibiotic, CB-25-I, was isolated from the culture broth of a strain of Serratia plymuthica. The antibiotic, a water-soluble dipeptide, is structurally related to Sch 37137 and A 19009, both produced by strains of Actinomycetales. The antibiotic exhibits inhibitory activity against Candida albicans in YNB medium (a synthetic medium), but the activity is significantly reduced in Sabouroud dextrose medium.