Interoceptive predictions in the brain.
Interoceptive predictions in the brain.
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DOI：
10.1038/nrn3950
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发表时间：
2015-07
期刊：
影响因子：
--
通讯作者：
Simmons WK
中科院分区：
文献类型：
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作者：
Barrett LF;Simmons WK
直觉表明，感知跟随感觉产生，因此身体的感觉源于身体本身。然而，近期的证据与这一逻辑相悖：内感受体验可能在很大程度上反映了边缘系统对身体预期状态的预测，而这种预测受到上升的内脏感觉的限制。在这篇观点文章中，我们介绍了具身预测性内感受编码模型，该模型将皮质间连接的解剖模型与贝叶斯主动推理原理相结合，提出无颗粒内脏运动皮质通过发出内感受预测来促进内感受。然后，我们讨论了内感受预测的中断如何可能成为精神和身体疾病的一个常见易感性因素。
Intuition suggests that perception follows sensation and therefore bodily feelings originate in the body. However, recent evidence goes against this logic: interoceptive experience may largely reflect limbic predictions about the expected state of the body that are constrained by ascending visceral sensations. In this Opinion article, we introduce the Embodied Predictive Interoception Coding model, which integrates an anatomical model of corticocortical connections with Bayesian active inference principles, to propose that agranular visceromotor cortices contribute to interoception by issuing interoceptive predictions. We then discuss how disruptions in interoceptive predictions could function as a common vulnerability for mental and physical illness.