Low birth weight and neurocognitive status at six years of age
Low birth weight and neurocognitive status at six years of age
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DOI：
10.1016/0006-3223(95)00399-1
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发表时间：
1996-09-01
影响因子：
10.6
通讯作者：
Brown, G
中科院分区：
文献类型：
--
作者：
Breslau, N;Chilcoat, H;Brown, G
我们在一项大规模的非同期前瞻性研究中研究了低出生体重（LBW）（小于或等于2500 g）与6岁时特定神经认知能力之间的关系。在1990年至1992年，我们随机选择和评估LBW和正常出生体重（NBW）的儿童从1983年至1985年的新生儿名单在密歇根州东南部的两个主要医院，一个缝合城市和其他郊区人口。LBW儿童（n = 473）在测量语言，空间，精细运动，触觉和注意力能力的测试中得分显著低于NEW儿童（n = 350），控制人口地点，种族，母亲智商和教育，在语言，空间，触觉和注意力测试中观察到LBW水平的梯度关系。探索性分析，使用一般添加剂模型，显示，测试性能不同的出生体重水平和性能继续提高出生体重远高于3000克。随着儿童的成熟，后续评估将揭示这些关联的持续性及其对学习障碍的影响。
We examined the relationship between low birth weight (LBW) (less than or equal to 2500 g) and specific neurocognitive abilities at 6 years of age in a large-scale nonconcurrent prospective study. In 1990-1992, we randomly selected and evaluated LBW and normal birth weight (NBW) children from the 1983-1985 newborn lists of two major hospitals in southeast Michigan, one sewing an urban and the other a suburban population. LBW children (n = 473) scored significantly lower than NEW children (n = 350) on tests measuring language, spatial, fine motor, tactile, and attention abilities, controlling for population site, race, maternal IQ, and education, Gradient relationships were observed across levels of LBW with language, spatial, tactile, and attention tests. Exploratory analysis, using general additive models, revealed that test performance varied within birth weight levels and that performance continued to improve with increased birth weight well above 3000 g. Follow-up assessments as the children mature will shed light on the persistence of these associations and their implications for learning disorders.