Developmental Trajectories in Siblings of Children with Autism: Cognition and Language from 4 Months to 7 Years
Developmental Trajectories in Siblings of Children with Autism: Cognition and Language from 4 Months to 7 Years
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DOI：
10.1007/s10803-009-0727-2
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发表时间：
2009-08-01
影响因子：
3.9
通讯作者：
Sigman, Marian
中科院分区：
文献类型：
--
作者：
Gamliel, Ifat;Yirmiya, Nurit;Sigman, Marian
采用生长曲线分析方法，比较了自闭症儿童（SIBS-A）和典型发育儿童（SIBS-TD）兄弟姐妹在4、14、24、36、54个月和7岁时的认知和语言发育。在7岁时，通过直接测试和/或父母报告，40%的SIBS-A儿童被确定为认知、语言和/或学业困难，而SIBS-TD儿童的这一比例为16%。该亚群被鉴定为SIBS-A-broad表型（BP）。结果表明，与SIBS-TD相比，SIBS-A- bp和SIBS-A-非bp的早期语言得分（14-54个月）显著低于SIBS-TD，但认知得分不显著低于SIBS-TD，而且发展速度也有显著差异，从而明确了语言是学龄前SIBS-A的主要困难领域。
We compared the cognitive and language development at 4, 14, 24, 36, 54 months, and 7 years of siblings of children with autism (SIBS-A) to that of siblings of children with typical development (SIBS-TD) using growth curve analyses. At 7 years, 40% of the SIBS-A, compared to 16% of SIBS-TD, were identified with cognitive, language and/or academic difficulties, identified using direct tests and/or parental reports. This sub-group was identified as SIBS-A-broad phenotype (BP). Results indicated that early language scores (14-54 months), but not cognitive scores of SIBS-A-BP and SIBS-A-nonBP were significantly lower compared to the language scores of SIBS-TD, and that the rate of development was also significantly different, thus pinpointing language as a major area of difficulty for SIBS-A during the preschool years.