Programmed synthesis of freestanding graphene nanomembrane arrays.
Programmed synthesis of freestanding graphene nanomembrane arrays.
复制标题
DOI：
10.1002/smll.201402230
复制
发表时间：
2015-02-04
期刊：
影响因子：
--
通讯作者：
Wanunu M
中科院分区：
文献类型：
--
作者：
Waduge P;Larkin J;Upmanyu M;Kar S;Wanunu M
独立石墨烯膜是一种独特的材料。原子薄的尺寸、卓越的机械坚固性和化学稳定性的结合，使多孔和非多孔石墨烯膜在水净化和各种传感应用中具有吸引力。基于横向DNA基控电流或通孔离子电流的读数，石墨烯和其他二维材料中的纳米孔已被确定为下一代DNA测序的有前途的设备。虽然已经报道了几项用于DNA分析的基于石墨烯纳米孔的突破性研究，但迄今为止报道的所有方法都需要将石墨烯从其生产来源物理转移到孔径支架上。转移过程缓慢，经常导致石墨烯撕裂，使许多设备无法用于纳米孔测量。在这项工作中，我们报告了一种新的可扩展的方法，用于现场定向制造无针孔石墨烯纳米膜。我们的方法在不到一天的时间内生产出高质量的几层石墨烯纳米膜，使用的几个步骤不涉及转移。我们通过电子束在这种膜上制造纳米孔来测量DNA易位，从而突出了这些石墨烯装置的功能。
Freestanding graphene membranes are unique materials. The combination of atomically thin dimensions, remarkable mechanical robustness, and chemical stability, make porous and non-porous graphene membranes attractive for water purification and various sensing applications. Nanopores in graphene and other 2D materials have been identified as promising devices for next-generation DNA sequencing, based on readout of either transverse DNA base-gated current or through-pore ion current. While several ground breaking studies of graphene-based nanopores for DNA analysis have been reported, all methods reported to date require a physical transfer of the graphene from its source of production onto an aperture support. The transfer process is slow and often leads to tears in the graphene that render many devices useless for nanopore measurements. In this work, we report a novel scalable approach for site-directed fabrication of pinhole-free graphene nano-membranes. Our approach yields high quality few-layer graphene nano-membranes produced in less than a day using a few steps that do not involve transfer. We highlight the functionality of these graphene devices by measuring DNA translocation through electron-beam fabricated nanopores in such membranes.