DENGUE EPIDEMICS ON THE PACIFIC COAST OF MEXICO
DENGUE EPIDEMICS ON THE PACIFIC COAST OF MEXICO
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DOI：
10.1093/ije/17.1.178
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发表时间：
1988-03-01
影响因子：
7.7
通讯作者：
MIRELLES, ER
中科院分区：
文献类型：
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作者：
DANTES, HG;KOOPMAN, JS;MIRELLES, ER
对墨西哥三个城市的登革热疫情进行了回顾性调查，并从急性病例中分离出病毒。这些流行病是自1978年以来登革热在墨西哥持续蔓延的一部分，此前15年没有传播。在所有疫情中，血清1型登革热感染占主导地位，但在一个城市，也分离到2型毒株。以下结果在所有三个城市都是一致的：1)在疫情出现前几个月，疾病病史提供了存在感染的证据；2)登革热发病率按年龄急剧递增；3)疾病与家庭中不同类型的养殖场之间没有可解释的关系；4)社会经济状况与疾病呈强烈负相关；5)与其他测量变量无关的地理因素对反映传播焦点的发病率有很大影响。此外，有证据表明，使用蚊帐或在房屋上安装屏风对疾病有很强的保护作用，但这些关系并不是所有三个城市都普遍存在的。
Dengue epidemics in three Mexican cities were investigated with retrospective surveys and virus isolations from acute cases. These epidemics were part of the continuing extension of dengue in Mexico since 1978 after 15 years without transmission. Serotype 1 dengue infection predominated in all epidemics, but in one city, type 2 strains were also isolated. The following findings were consistent in all three cities: 1) illness history provided evidence of presence of infection months before the epidemic became evident 2) there was a very sharp and progressive increase of dengue illness attack rates by age, 3) there were no interpretable relationships between illness and the presence of different types of breeding sights in the home, 4) socioeconomlc status was strongly negatively related to illness, and 5) geographical factors not related to the other measured variables had a strong effect on illness rates reflecting the focality of transmission. In addition, there was evidence of a strong protective effect against illness by the use of mosquito netting or the presence of screens on houses, but these relationships were not universal to all three cities.