The biomechanical effect of vertebroplasty on the adjacent vertebral body: a finite element study
The biomechanical effect of vertebroplasty on the adjacent vertebral body: a finite element study
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DOI：
10.1243/09544119h00305
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发表时间：
2006-05-01
期刊：
影响因子：
1.8
通讯作者：
Wilcox, R. K.
中科院分区：
文献类型：
--
作者：
Wilcox, R. K.
越来越多的椎体成形术用于治疗骨质疏松性椎体压缩骨折，这引起了人们的担忧，即该技术可能会增加邻近椎体骨折的风险。本研究的目的是使用骨质疏松的双椎体有限元模型来模拟椎体成形术的生物力学效应。在模拟压缩骨折后，在模型中添加三种体积的PMMA基水泥中的一种，或者不进行处理。在重新加载时，发现随着水泥体积的增加，节段刚度增加。然而，在所有接受治疗的模型中，终板向邻近椎体的偏转增加，导致周围骨小梁的塑性失效。与未治疗的模型相比，治疗的模型对邻近椎体造成的损伤更大。模型结果表明，临床医生应该警惕使用标准的椎体成形术水泥治疗高度骨质疏松患者的压缩骨折。
The increased use of vertebroplasty for the treatment of osteoporotic vertebral compression fractures has led to concerns that the technique may increase the risk of fracture in the adjacent vertebrae. The aim of this study was to simulate the biomechanical effects of vertebroplasty using an osteoporotic two-vertebrae finite element model. Following a simulated compression fracture, the model was augmented with one of three volumes of PMMA-based cement or left untreated. Upon reloading, an increase in segment stiffness was found with increasing volumes of cement. However, in all the treated models there was an increase in endplate deflection into the adjacent vertebra causing plastic failure of the surrounding trabecular bone. More damage was caused in the adjacent vertebra of the treated models than in the untreated model. The model results suggest that clinicians should be wary of using standard vertebroplasty cements to treat compression fractures in patients with highly osteoporotic bone.