Concise and practical synthesis of latrunculin A by ring-closing enyne-yne metathesis
Concise and practical synthesis of latrunculin A by ring-closing enyne-yne metathesis
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DOI：
10.1002/anie.200500390
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发表时间：
2005-01-01
影响因子：
16.6
通讯作者：
Turet, L
中科院分区：
文献类型：
--
作者：
Fürstner, A;Turet, L
Selective actin-binding is the most prominent biochemical property of the scarce marine natural product latrunculin A (see formula). Modern metal-catalyzed CC bond-formation reactions, including a ring-closing enyne–yne metathesis (shown in red), now open a convenient, flexible, and productive entry to this important probe molecule for chemical biology.
