Sleep-related consolidation of a visuomotor skill: Brain mechanisms as assessed by functional magnetic resonance imaging
Sleep-related consolidation of a visuomotor skill: Brain mechanisms as assessed by functional magnetic resonance imaging
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DOI：
10.1523/jneurosci.23-04-01432.2003
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发表时间：
2003-02-15
影响因子：
5.3
通讯作者：
Frith, C
中科院分区：
文献类型：
--
作者：
Maquet, P;Schwartz, S;Frith, C
受试者接受了追踪任务的训练，在该任务中，目标轨迹只在水平轴上是可预测的。其中半数受试者在训练后第一晚睡眠不足(n=13)。三天后，功能磁共振成像显示，与新轨迹相比，学习轨迹的大脑反应与任务相关。睡眠组(n=12)与睡眠剥夺组相比，被试的表现有所改善，其在颞叶上沟(STS)的脑活动更强。观察到STS和小脑之间以及辅助眼场和额眼视场之间的功能连接增加。这些差异表明，在运动技能学习过程中，与睡眠相关的可塑性变化涉及到平稳追逐眼球运动的区域。
Subjects were trained on a pursuit task in which the target trajectory was predictable only on the horizontal axis. Half of them were sleep deprived on the first post-training night (n = 13). Three days later, functional magnetic resonance imaging revealed task-related increases in brain responses to the learned trajectory, as compared with a new trajectory. In the sleeping group (n = 12) as compared with the sleep-deprived group, subjects' performance was improved, and their brain activity was greater in the superior temporal sulcus (STS). Increased functional connectivity was observed between the STS and the cerebellum and between the supplementary eye field and the frontal eye field. These differences indicate sleep-related plastic changes during motor skill learning in areas involved in smooth pursuit eye movements.