Medical marijuana: clearing away the smoke.
Medical marijuana: clearing away the smoke.
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DOI：
10.2174/1874205x01206010018
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Wilsey B
中科院分区：
文献类型：
--
作者：
Grant I;Atkinson JH;Gouaux B;Wilsey B
最近在了解大麻的四氢大麻酚和相关大麻素合成物的作用方式方面取得了进展，加上关于潜在医疗益处的越来越多的轶事报道，促使人们越来越多地研究大麻的可能药用。最近的临床试验与烟熏和汽化大麻，以及其他植物提取物表明，大麻素可能是有用的神经性疼痛，痉挛由于多发性硬化症的管理，并可能其他适应症。与所有药物一样，在向患者推荐大麻时需要权衡利益和风险。我们提出了一个算法，可能是有用的医生在确定是否大麻可能被推荐作为一种治疗在司法管辖区，这种使用是允许的。
Recent advances in understanding of the mode of action of tetrahydrocannabinol and related cannabinoid in-gredients of marijuana, plus the accumulating anecdotal reports on potential medical benefits have spurred increasing re-search into possible medicinal uses of cannabis. Recent clinical trials with smoked and vaporized marijuana, as well as other botanical extracts indicate the likelihood that the cannabinoids can be useful in the management of neuropathic pain, spasticity due to multiple sclerosis, and possibly other indications. As with all medications, benefits and risks need to be weighed in recommending cannabis to patients. We present an algorithm that may be useful to physicians in determining whether cannabis might be recommended as a treatment in jurisdictions where such use is permitted.