Behavioral activation, inhibition and mood symptoms in early-onset bipolar disorder
Behavioral activation, inhibition and mood symptoms in early-onset bipolar disorder
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DOI：
10.1016/j.jad.2006.07.005
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发表时间：
2007-01-01
影响因子：
6.6
通讯作者：
Kim, Eunice Y.
中科院分区：
文献类型：
--
作者：
Biuckians, Adrine;Miklowitz, David J.;Kim, Eunice Y.
背景资料：轻躁狂/躁狂和抑郁被假设分别对应于双相情感障碍患者行为激活系统（BAS）活性的高表达和低表达。相反，行为抑制系统（BIS）的活动被假设为调节焦虑。本研究的目的是检查是否自我报告的水平BAS功能在双相青少年对应的水平，同时躁狂和抑郁抑郁症。次要目的是调查自我报告的BIS水平是否与自我报告的焦虑symptoms.Methods：25名青少年诊断为双相1，11或未另行说明招募治疗发展研究。青少年进行了采访，使用儿童情感障碍和精神分裂症的时间表的抑郁和躁狂量表，并给出了儿童焦虑相关疾病的自我报告。接下来，他们完成了行为抑制/激活Scales.Results：与假设相反，青少年与较高的BAS水平表现出较轻的并发躁狂症状。此外，BAS敏感性水平与并发抑郁水平无关。正如预测的那样，BIS分数与自我报告的焦虑分数呈正相关。青少年报告较高水平的运动活动症状的躁狂症也报告较高水平的焦虑symptoms.Limitations：的结论是基于在一个小样本的横断面分析。结论：在双相青少年，躁狂症和抑郁症似乎是独立的自我报告的行为激活水平。然而，青少年患者的情绪症状与焦虑成分密切相关，这可能导致接近行为减少。(c)2006 Elsevier B. V.保留所有权利。
Background: Hypomania/mania and depression are hypothesized to correspond to high and low expressions of behavioral activation system (BAS) activity, respectively, in bipolar individuals. In contrast, behavioral inhibition system (BIS) activity is hypothesized to regulate anxiety. The aim of the present study was to examine whether self-reported levels of BAS functioning in bipolar adolescents corresponded with levels of concurrent manic and depressive symptomatology. The secondary aim was to investigate whether self-reported BIS levels were associated with self-reported anxiety symptoms.Methods: Twenty-five adolescents diagnosed with bipolar 1, 11 or not otherwise specified were recruited from a treatment-development study. Adolescents were interviewed using the Depression and Mania Rating Scales of the Kiddie Schedule for Affective Disorders and Schizophrenia and given the Self-Report for Childhood Anxiety Related Disorders. Next, they completed the Behavioral Inhibition/Activation Scales.Results: Contrary to hypotheses, adolescents with higher BAS levels exhibited less severe concurrent mania symptoms. Furthermore, levels of BAS sensitivity were not associated with concurrent levels of depression. As predicted, BIS scores correlated positively with self-reported anxiety scores. Adolescents reporting higher levels of the motor activity symptoms of mania also reported higher levels of anxiety symptoms.Limitations: The conclusions are based upon cross-sectional analyses in a small sample.Conclusions: In bipolar adolescents, mania and depression appear to be independent of self-reported behavioral activation levels. However, mood symptoms in adolescent patients are closely tied to components of anxiety, which may lead to diminished approach behaviors. (c) 2006 Elsevier B.V. All rights reserved.