Comparison of platelet count and platelet protein methods for determination of platelet MAO activity.

Comparison of platelet count and platelet protein methods for determination of platelet MAO activity.
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血小板计数法和血小板蛋白法测定血小板 MAO 活性的比较。

DOI:
10.1016/0009-8981(79)90047-0
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发表时间:
1979
期刊:
Clinica chimica acta; international journal of clinical chemistry
影响因子:
--
通讯作者:
H. Meltzer
H. Meltzer
中科院分区:
--
文献类型:
--
作者:
H. Jackman;Ramesh Chandra Arora;H. Meltzer

文献摘要

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研究了10名正常志愿者血小板单胺氧化酶(MAO)活性与血小板蛋白或电子测定血小板计数的关系。对当天和一周后检测的样品进行了两种方法的比较。两种方法得到的MAO活性结果具有显著的相关性和可重复性,但血小板计数法的结果在大多数情况下比血小板蛋白法的结果略微但显著地更可靠。讨论了这些结果与精神分裂症患者血小板MAO活性争议的相关性。
Platelet monoamine oxidase (MAO) activity in 10 normal volunteers was studied as a function of platelet protein or electronically-determined platelet counts. Comparisons of the two methods were made for samples assayed on the same day as well as one week later. The MAO activities resulting from both methods were significantly correlated and reproducible but the results of the platelet count method were, in most instances, slightly but significantly more reliable than the platelet protein method. The relevance of these results to the controversy concerning platelet MAO activity in schizophrenia is discussed.