The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.

The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.
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酰胺酶的机制:使催化三联体附近的谷氨酸发生突变,由于底物错位而使酶失活。

DOI:
10.1074/jbc.m113.503284
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发表时间:
2013
期刊:
The Journal of biological chemistry
影响因子:
--
通讯作者:
Sewell,BTrevor
Sewell,BTrevor
中科院分区:
--
文献类型:
--
作者:
Weber,BrandonW;Kimani,SerahW;Varsani,Arvind;Cowan,DonaldA;Hunter,Roger;Venter,GerhardA;Gumbart,JamesC;Sewell,BTrevor

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