Injection of nanoparticles into cloven-hoof animals: Asking for trouble.

Injection of nanoparticles into cloven-hoof animals: Asking for trouble.
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DOI:
10.7150/thno.22420
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发表时间:
2017
期刊:
影响因子:
12.4
通讯作者:
Skotland T
Skotland T
中科院分区:
医学1区
文献类型:
--
作者:
Skotland T

文献摘要

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这篇文章旨在提醒从事纳米颗粒或微粒研究的科学家,猪和其他偶蹄动物体内存在的血管内肺巨噬细胞导致的特定不良反应,但不是人类。一项已有25年历史的超声造影剂研究历史被用来说明这些差异。
This article aims at alerting scientists working with nanoparticles or microparticles about the specific adverse reactions due to the intravascular pulmonary macrophages present in pigs and other cloven-hoof animals, but not in humans. The history of a 25-year old study of an ultrasound contrast agent is used to illustrate these differences.