IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation
IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation
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DOI：
10.1159/000506975
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发表时间：
2020-04
影响因子：
0.8
通讯作者：
Saaya Yoshida;T. Fujimura;K. Ohuchi;Y. Kambayashi;Yuichiro Segawa;E. Yamazaki;Hisayuki Tono;Toshiya Takahashi;K. Tsuchiyama;S. Aiba
中科院分区：
文献类型：
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作者：
Saaya Yoshida;T. Fujimura;K. Ohuchi;Y. Kambayashi;Yuichiro Segawa;E. Yamazaki;Hisayuki Tono;Toshiya Takahashi;K. Tsuchiyama;S. Aiba
Stewart-Treves综合征（STS）是一种罕见的皮肤淋巴管肉瘤，由于根治性乳房切除术或手术侵入腹股沟治疗宫颈癌或阴茎癌而导致慢性淋巴水肿。以往的研究表明，淋巴管肉瘤的发生可能与STS患者的免疫学背景有关。在这篇报告中，我们描述了两例因子宫颈癌行根治性切除术后发生STS的病例，我们采用了IL-23和IL-17的免疫组织化学染色。
Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17.