Human brain activation during passive listening to sounds from different locations: An fMRI and MEG study
Human brain activation during passive listening to sounds from different locations: An fMRI and MEG study
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DOI：
10.1002/hbm.20164
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发表时间：
2005-12-01
影响因子：
4.8
通讯作者：
Romani, GL
中科院分区：
文献类型：
--
作者：
Brunetti, M;Belardinelli, P;Romani, GL
最近的动物和人类的研究表明，存在一个神经通路的声音定位，这是类似于“在哪里”的视觉系统的路径，并从声音识别路径不同。这项研究试图强调这一途径使用被动倾听协议。我们采用功能磁共振成像来研究皮层区域，激活过程中的声音来自不同的位置，和脑磁图揭示这些地区的时间动态。此外，不同的激活水平在右半球和左半球的假设，由于大脑半球的专业化，进行了调查。功能磁共振成像的结果表明，来自不同位置的声音的处理激活了一个复杂的中性音回路，类似于猴子的声音定位系统，称为听觉“哪里”通路。该系统包括Heschl's gyrus、上级颞回、缘上回以及下额叶和中额叶。MEG分析允许评估该回路的时间：听觉刺激后139 ms观察到Heschl's回的激活，位于上级颞回的源的峰值潜伏期为156 ms，顶下小叶和缘上回的峰值潜伏期为162 ms。发现两个半球都参与处理来自不同位置的声音，但在右半球观察到更强的激活。
Recent animal and human studies indicate the existence of a neural pathway for sound localization, which is similar to the "where" pathway of the visual system and distinct from the sound identification pathway. This study sought to highlight this pathway using a passive listening protocol. We employed fMRI to study cortical areas, activated during the processing of sounds coming from different locations, and MEG to disclose the temporal dynamics of these areas. In addition, the hypothesis of different activation levels in the right and in the left hemispheres, due to hemispheric specialization of the human brain, was investigated. The fMRI results indicate that the processing of sound, coming from different locations, activates a complex neutonal circuit, similar to the sound localization system described in monkeys known as the auditory "where" pathway. This system includes Heschl's gyrus, the superior temporal gyrus, the supramarginal gyrus, and the inferior and middle frontal lobe. The MEG analysis allowed assessment of the timing of this circuit: the activation of Heschl's gyrus was observed 139 ms after the auditory stimulus, the peak latency of the source located in the superior temporal gyrus was at 156 ms, and the inferior parietal lobule and the supramarginal gyrus peaked at 162 ms. Both hemispheres were found to be involved in the processing of sounds coming from different locations, but a stronger activation was observed in the right hemisphere.