From Structural Disparities to Neuropharmacology: A Review of Adult Attention-Deficit/Hyperactivity Disorder Medication Treatment.
From Structural Disparities to Neuropharmacology: A Review of Adult Attention-Deficit/Hyperactivity Disorder Medication Treatment.
复制标题
从结构差异到神经药理学：成人注意力缺陷/多动症药物治疗的回顾。
DOI：
10.1016/j.chc.2022.03.002
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发表时间：
2022
影响因子：
2.4
通讯作者：
Faraone,StephenV
中科院分区：
文献类型：
--
作者：
Khoury,NaylaM;Radonjić,NevenaV;Albert,AveryB;Faraone,StephenV
ADHD是一种早发性疾病，伴有许多功能障碍和精神共病。虽然没有治疗完全减轻与ADHD相关的损害，但通过药物和非药物治疗可以有效管理。ADHD的病因学和病理生理学非常复杂，并且这种疾病在人群中持续分布。虽然这些发现在以白色样本为主的研究中得到了很好的证明，但由于诊断和治疗的差异，ADHD可能会对种族和少数民族产生不同的影响。这篇综述提供了ADHD的流行病学、病因学、神经生物学和神经药理学的最新概述，并在有数据的情况下解决了种族和民族差异。
ADHD is an early-onset disorder with many functional impairments and psychiatric comorbidities. Although no treatment fully mitigates impairments associated with ADHD, effective management is possible with pharmacologic and non-pharmacologic treatments. The etiology and pathophysiology of ADHD are remarkably complex and the disorder, is continuously distributed in the population. While these findings have been well documented in studies with predominantly white samples, ADHD may affect racial and ethnic minorities differentially, given diagnostic and treatment disparities. This review provides an updated overview of the epidemiology, etiology, neurobiology, and neuropharmacology of ADHD, addressing racial and ethnic disparities where data are available.