Regression of salivary gland MALT lymphoma after treatment for Helicobacter pylori
Regression of salivary gland MALT lymphoma after treatment for Helicobacter pylori
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幽门螺杆菌治疗后唾液腺 MALT 淋巴瘤的消退
DOI：
10.1016/s0140-6736(05)65578-x
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
P. Cohen
中科院分区：
文献类型：
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作者：
S. Alkan;D. Karcher;Michael A Newman;P. Cohen
SIR——胃肠道的原发性淋巴瘤可能起源于粘膜淋巴细胞，是所有结外淋巴瘤中最大的群体。 1 24% 的病例起源于胃，10% 起源于小肠，7% 起源于结肠和直肠，11% 起源于韦氏环。 1 粘膜相关淋巴组织 (MALT) 淋巴瘤是淋巴瘤的一种亚型。 1-3 胃 MALT 淋巴瘤与粘膜幽门螺杆菌感染有因果关系。胃肠道其他部位（如十二指肠、回肠和结肠）也有 MALT 淋巴瘤的报道。我们报告累及食管的 MALT 淋巴瘤。一名 61 岁男性因胃窦溃疡出现上消化道出血。他有幽门螺杆菌感染的证据，除雷尼替丁外，还接受了甲硝唑、四环素和次水杨酸铋治疗。重复上消化道内镜检查显示结节状胃窦肿块。活检显示 MALT 淋巴瘤。没有发现幽门螺杆菌感染的证据。他开始服用克拉霉素和兰索拉唑，并转介给我们进行进一步评估。内窥镜检查显示胃窦结节性肿块（22 厘米）、胃底息肉样肿块（23 厘米）和两个线性凸起病变（12 厘米），近端粘膜明显正常
SIR—Primary lymphomas of the gastrointestinal tract probably originate from mucosal lymphocytes and represent the largest group of all extranodal lymphomas. 1 They originate in the stomach in 24% of cases, in the small bowel in 10%, in the colon and rectum in 7%, and in Waldeyer’s ring in 11%. 1 Mucosa-associated lymphoid tissue (MALT) lymphoma, is a subtype of lymphoma. 1–3 Gastric MALT lymphoma has been causally linked to mucosal Helicobacter pylori infection. MALT lymphomas have been reported in other parts of the gastrointestinal tract, such as the duodenum, ileum, and colon. We report MALT lymphoma involving the oesophagus.A 61-year-old man had an episode of upper gastrointestinal bleeding from a gastric antral ulcer. He had evidence of H pylori infection and was treated with metronidazole, tetracycline, and bismuth subsalicylate in addition to ranitidine. Repeat upper gastrointestinal endoscopy showed a nodular antral mass. Biopsies indicated MALT lymphoma. No evidence of H pylori infection was found. He was started on clarithromycin and lansoprazole and referred to us for further evaluation. Endoscopy showed an antral nodular mass (22 cm), fundic polypoid mass (23 cm), and two linear raised lesions (12 cm) with apparently normal overlying mucosa in the proximal