CLINICAL AND EPIDEMIOLOGIC STUDIES OF PNEUMOCOCCAL INFECTION IN CHILDREN
CLINICAL AND EPIDEMIOLOGIC STUDIES OF PNEUMOCOCCAL INFECTION IN CHILDREN
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DOI：
10.1097/00006454-198603000-00009
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发表时间：
1986-03-01
影响因子：
3.6
通讯作者：
DILLON, HC
中科院分区：
文献类型：
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作者：
GRAY, BM;DILLON, HC
肺炎链球菌：从1979年至1984年的5年期间从1310名儿童中分离出来。有44例脑膜炎、172例菌血症感染、787例中耳炎和307例呼吸道和其他分离株。大多数感染可由少数血清型引起，其中以3、6、14、19和23型为主。大多数感染（70%）发生在2岁以下的婴儿中。然而，近四分之一的全身性疾病患者有一些潜在的疾病，这可能导致他们感染的风险，甚至超过2岁。12例死亡中有10例发生在宿主防御改变的患者中。肺炎球菌疾病的特点和血清型的分布进行了讨论，在过去的50年中，其他调查人员的工作。
Streptococcus pneumoniae: was isolated from 1310 children in a 5-year period from 1979 through 1984. There were 44 cases of meningitis, 172 bacteremic infections, 787 cases of otitis media and 307 respiratory and miscellaneous isolates. The majority of infections could be accounted for by a small number of serotypes, with types 3, 6, 14, 19 and 23 predominating. Most infections (70%) occurred in infants younger than 2 years of age. However, nearly one-fourth of those suffering systemic illness had some underlying condition which may have contributed to their risk for infection, even beyond 2 years of age. Ten of the 12 deaths occurred in patients with altered host defenses. Characteristics of pneumococcal disease and the distribution of serotypes are discussed in relation to the work of other investigators over the past 50 years.