Utility of animal models for human embryo culture: nonhuman primates.

Utility of animal models for human embryo culture: nonhuman primates.
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人类胚胎培养动物模型的实用性:非人类灵长类动物。

DOI:
10.1007/978-1-61779-971-6_4
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发表时间:
2012
期刊:
Methods in molecular biology (Clifton, N.J.)
影响因子:
--
通讯作者:
Schatten,Gerald
Schatten,Gerald
中科院分区:
--
文献类型:
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作者:
Simerly,Calvin;Schatten,Gerald

文献摘要

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非人类灵长类动物是人类最亲近的亲戚,因此也是我们进化上最接近的近亲。虽然通过研究啮齿动物和其他系统获得了惊人的见解,但不可能想象如何在不适当使用非人类灵长类动物的情况下将这些机械发现负责任地转化为临床。值得庆幸的是,非侵入性技术现在允许进行非人类灵长类动物研究,而不会危及模型本身。预计在二十一世纪余下的时间里,灵长类动物的研究将继续引领生殖和再生医学领域。
Nonhuman primates are the closest relatives to humans and therefore our most evolutionary close cousins. While marvelous insights are gleaned from studying rodents and other systems, it is impossible to envision how those mechanistic findings can be responsibly translated to the clinic without the appropriate use of nonhuman primates. Thankfully, noninvasive technologies now permit nonhuman primate studies without endangering the model itself. Work with primates is predicted to continue to lead the fields of reproductive and regenerative medicine for the rest of the twenty-first century.