DOG RED BLOOD-CELLS - ADJUSTMENT OF DENSITY IN-VIVO
DOG RED BLOOD-CELLS - ADJUSTMENT OF DENSITY IN-VIVO
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DOI：
10.1085/jgp.61.2.146
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发表时间：
1973-01-01
影响因子：
3.8
通讯作者：
PARKER, JC
中科院分区：
文献类型：
--
作者：
PARKER, JC
Red blood cells from mature dogs contain less Na and more K than would be the case if they were in Donnan equilibrium with plasma. They have no ouabain-sensitive Na pump, and their membranes are deficient in Na, K-ATPase. Experiments are reported in which dog red cells were first loaded with supranormal quantities of Na and water and then reinjected into the dog. Over the course of 26-40 h the Na-and water-loaded cells returned to a normal state of hydration as judged by their density. It is concluded that dog red cells possess some means of correcting their swollen status in vivo, despite their lack of a ouabain-sensitive cation transport apparatus.
