A Population-Based Study of Visual Inspection With Acetic Acid (VIA) for Cervical Screening in Rural Nigeria
A Population-Based Study of Visual Inspection With Acetic Acid (VIA) for Cervical Screening in Rural Nigeria
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DOI：
10.1097/igc.0b013e318280f395
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发表时间：
2013-03-01
影响因子：
4.8
通讯作者：
Schiffman, Mark
中科院分区：
文献类型：
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作者：
Ajenifuja, Kayode Olusegun;Gage, Julia C.;Schiffman, Mark
目的：宫颈癌是发展中国家最常见的妇科恶性肿瘤。在发展中国家，由于许多国家无法实施高质量的细胞学服务，采用醋酸目视检查（VIA）筛查宫颈癌前病变。我们试图比较不同的卫生工作者之间的VIA性能在尼日利亚。方法：在一个以人口为基础的项目中，7名卫生工作者谁一直在筛选妇女与VIA约2年在当地政府卫生中心在农村尼日利亚进行了再培训，在一个为期2周的计划，使用国际癌症研究机构的培训手册。来自一个从未进行过宫颈癌筛查的农村妇女被招募到研究中。每个女人都有宫颈癌筛查VIA，液基细胞学检查，致癌的人乳头瘤病毒（HPV）DNA test.Results：尽管相似的参与者的特点，在所有年龄组，供应商有广泛的VIA结果，0%至21%的可疑癌症和0%至25%的VIA阳性。与乙酸的目视检查是不敏感的细胞学和HPV tests.Conclusion相结合：在我们的研究中，VIA是不可重复的，也不是敏感的细胞学和HPV检测相比。
Objective: Cervical cancer is the most common gynecological cancer in developing countries. Visual inspection with acetic acid (VIA) was introduced to screen for cervical premalignant lesions in developing countries owing to the inability of many countries to implement high-quality cytologic services. We sought to compare VIA performance among different health workers in Nigeria.Methods: In a population-based project, 7 health workers who had been screening women with VIA for approximately 2 years at local government health centers in rural Nigeria were retrained in a 2-week program using the International Agency for Research on Cancer training manual. Women from a rural village who had never had cervical cancer screening were recruited into the study. Each woman had cervical cancer screening by VIA, liquid-based cytologic test, and oncogenic human papillomavirus (HPV) DNA test.Results: Despite similar participant characteristics, across all age groups, providers had wide ranges of VIA results; 0% to 21% suspect cancer and 0% to 25% were VIA positive. Visual inspection with acetic acid was insensitive compared to a combination of cytologic and HPV tests.Conclusion: In our study, VIA was not reproducible, nor was it sensitive compared to cytologic and HPV tests.