MODIFICATION OF BACTERIAL RESPIRATION BY A MACROMOLECULAR POLYANIONIC ANTIBIOTIC PRODUCED BY A MARINE ALTEROMONAS
MODIFICATION OF BACTERIAL RESPIRATION BY A MACROMOLECULAR POLYANIONIC ANTIBIOTIC PRODUCED BY A MARINE ALTEROMONAS
复制标题
DOI：
10.1128/aac.9.3.361
复制
发表时间：
1976-01-01
影响因子：
4.9
通讯作者：
GAUTHIER, MJ
中科院分区：
文献类型：
--
作者：
GAUTHIER, MJ
一种由属于交链单胞菌属的海洋细菌产生的大分子多阴离子抗生素，当加入到几种细菌生长的早期阶段的培养中时，会对细菌的呼吸产生很大的影响。这种抗生素导致氧气摄取增加和过氧化氢的产生。后一个事实解释了过氧化氢酶活性低的细菌的高敏感性和纯过氧化氢酶对抗生素的拮抗作用。这种抗生素可以通过建立黄色呼吸作用在呼吸链的水平上发挥作用。
A macromolecular polyanionic antibiotic produced by a marine bacterium belonging to the genusAlteromonascauses a large modification in bacterial respiration when added to the culture of several bacterial species in their early stage of growth. This antibiotic induces an increase of oxygen uptake and the production of hydrogen peroxide. The latter fact explains the high sensitivity of bacteria with low catalase activity and the antagonistic effect of pure catalase on antibiosis. The antibiotic could act at the level of the respiratory chain by setting up a flavinic respiration.