Effects of the Permeability of Shields with Autologous Bone Grafts on Bone Augmentation
Effects of the Permeability of Shields with Autologous Bone Grafts on Bone Augmentation
复制标题
DOI：
10.11607/jomi.te19
复制
发表时间：
2013-11-01
影响因子：
2
通讯作者：
Ueda, Minoru
中科院分区：
文献类型：
--
作者：
Ikeno, Masayuki;Hibi, Hideharu;Ueda, Minoru
目的：本研究的目的是在组织学上评价和比较屏蔽件的渗透性对兔颅骨模型中骨增量的影响。材料和方法：12只成年雄性日本白色家兔用于本研究。每个人都接受了四个钛圆柱体，将其放置在颅骨外皮质骨上制成的穿孔缝隙中，并填充有自体髂骨。圆柱体的顶部随机覆盖以下试验材料：（1）未覆盖（对照），（2）钛网，（3）膨胀型聚四氟乙烯（e-PTFE）膜，或（4）钛板。8周后，处死动物，获得研磨切片用于组织形态计量学分析。结果：各组增加的骨量无显著差异。然而，各组圆柱体中增强骨的分布不同。在未覆盖的对照组中，圆柱体上三分之一处的增强骨明显少于中间或下三分之一处。钛网组和e-PTFE膜组的结果相似，上三分之一的骨增强明显少于中三分之一或下三分之一。在钛板组中，上、中、下三分之一的骨增量无显著差异。按照钛板、e-PTFE膜、钛网和未覆盖对照的顺序，圆柱体上、中、下三分之一之间的差异较小。结论：使用低渗透性屏蔽导致当前骨增强模型中骨结构分布的微小差异。
Purpose: The objective of this study was to histologically evaluate and compare the effects of the permeability of shields on bone augmentation in a rabbit calvarial model. Materials and Methods: Twelve adult male Japanese white rabbits were used for the study. Each received four titanium cylinders, which were placed into perforated slits made in the outer cortical bone of the calvaria and filled with autologous iliac bone. The tops of the cylinders were randomly covered with the following test materials: (1) uncovered (control), (2) a titanium mesh, (3) an expanded polytetrafluoroethylene (e-PTFE) membrane, or (4) a titanium plate. After 8 weeks, the animals were sacrificed, and ground sections were obtained for histomorphometric analysis. Results: There was no significant difference in augmented bone volume among all groups. However, the distribution of augmented bone in the cylinders differed among the groups. In the uncovered control, there was significantly less augmented bone in the upper third of the cylinder than in the middle or lower thirds. Findings were similar for the titanium mesh group and the e-PTFE membrane group, with significantly less augmented bone in the upper third than in the middle or lower thirds. In the titanium plate group, there was no significant difference in augmented bone among the upper, middle, and lower thirds. The differences among the upper, middle, and lower thirds of the cylinder were smaller in the order of titanium plate, e-PTFE membrane, titanium mesh, and uncovered control. Conclusion: The use of low-permeability shields resulted in small differences in the distribution of bone structure in the present bone augmentation model.