Flavivirus susceptibility in Aedes aegypti
Flavivirus susceptibility in Aedes aegypti
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DOI：
10.1016/s0188-4409(02)00373-9
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发表时间：
2002-07-01
影响因子：
7.7
通讯作者：
Beaty, BJ
中科院分区：
文献类型：
--
作者：
Black, WC;Bennett, KE;Beaty, BJ
埃及伊蚊是世界范围内黄热病（YF）和登革热（DF）黄病毒的主要媒介。在这篇综述中，我们专注于过去和现在的研究埃及伊蚊的遗传成分和环境因素，似乎控制黄病毒传播。我们审查Ae之间的遗传关系。世界各地的埃及人种群，并讨论如何在载体能力的变化与种群之间的总体遗传差异。我们描述了目前的研究如何遗传和环境因素共同影响自然种群中的载体能力的分布。基于这些信息，我们提出了一个群体遗传模型的载体能力，并讨论了我们最近在测试这个模型的进展。最后，我们正在采取的方法来确定可能控制黄病毒易感性的基因在AE的讨论。埃及人。(C)2002年IMSS。爱思唯尔科学公司出版
Aedes aegypti is the primary vector of yellow fever (YF) and dengue fever (DF) flaviviruses worldwide. In this review we focus on past and present research on genetic components and environmental factors in Aedes aegypti that appear to control flavivirus transmission. We review genetic relationships among Ae. aegypti populations throughout the world and discuss how variation in vector competence is correlated with overall genetic differences among populations. We describe current research into how genetic and environmental factors jointly affect distribution of vector competence in natural populations. Based on this information, we propose a population genetic model for vector competence and discuss our recent progress in testing this model. We end with a discussion of approaches being taken to identify the genes that may control flavivirus susceptibility in Ae. aegypti. (C) 2002 IMSS. Published by Elsevier Science Inc.