Effects of NBm lesions on T-maze performance and thalamic biochemistry.

Effects of NBm lesions on T-maze performance and thalamic biochemistry.
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NBm 损伤对 T 迷宫性能和丘脑生物化学的影响。

DOI:
10.1016/0197-4580(93)90036-b
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发表时间:
1993
影响因子:
4.2
通讯作者:
Thal,LJ
Thal,LJ
中科院分区:
医学2区
文献类型:
--
作者:
Connor,DJ;Langdon,DJ;Langlais,PJ;Thal,LJ

文献摘要

相似文献

Fisher 344 rats underwent bilateral nucleus basalis magnocellularis (NBm) lesioning followed by testing in a delayed nonmatching-to-sample T-maze task. Both lesion and control animals acquired the task although the NBm animals were mildly impaired on acquisition and on trials to criterion. Increasing the delay reduced accuracy of performance equally in both groups. The NBm lesion did not alter the level of several thalamic amino acids. These data indicate that NBm lesioning does not produce a significant impairment in working or reference memory in this task and supports the hypothesis that NBm lesioning impairs attention.