Analysis of the aryl hydrocarbon receptor (AhR) signal transduction pathway.

Analysis of the aryl hydrocarbon receptor (AhR) signal transduction pathway.
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DOI:
10.1002/0471140856.tx0408s11
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发表时间:
2002-05-01
期刊:
Current protocols in toxicology
影响因子:
--
通讯作者:
Heath-Pagliuso, Sharon
Heath-Pagliuso, Sharon
中科院分区:
其他
文献类型:
--
作者:
Denison, Michael S;Rogers, Jane M;Heath-Pagliuso, Sharon

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Ah 受体信号转导通路分析(Michael S. Denison、Jane M. Rohers、S. Renee Rushing、Carol L. Jones、Selwyna C. Tetangico 和 Sharon Heath-Pagliuso,加州大学戴维斯分校)。本单元中的方案将允许研究人员在其生物测试系统中检测 Ah 受体并表征其功能活动(即配体结合、转化和 DNA 结合以及基因表达),并使用这些方法检测影响该信号系统的化学和生化事件。
Analysis of the Ah Receptor Signal Transduction Pathway (Michael S. Denison, Jane M. Rohers, S. Renee Rushing. Carol L. Jones, Selwyna C. Tetangico, and Sharon Heath-Pagliuso, University of California, Davis, California).The protocols in this unit will allow researchers to detect the Ah receptor and characterize its functional activities (i.e., ligand binding, transformation and DNA binding, and gene expression) in their biological test system and to use these methods to detect chemical and biochemical events that affect this signaling system.