A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
复制标题
功能性脑图谱的范式变化:抑制功能磁共振成像中的热噪声
DOI:
--
复制
发表时间:
2020
期刊:
影响因子:
--
通讯作者:
K. Uğurbil
中科院分区:
文献类型:
--
作者:
L. Vizioli;S. Moeller;Logan T Dowdle;M. Akçakaya;Federico De Martino;E. Yacoub;K. Uğurbil
Functional magnetic resonance imaging (fMRI) has become one of the most powerful tools for investigating the human brain. However, virtually all fMRI studies have relatively poor signal-to-noise ratio (SNR). We introduce a novel fMRI denoising technique, which removes noise that is indistinguishable from zero-mean Gaussian-distributed noise. Thermal noise, falling in this category, is a major noise source in fMRI, particularly, but not exclusively, at high spatial and/or temporal resolutions. Using 7-Tesla high-resolution data, we demonstrate remarkable improvements in temporal-SNR, the detection of stimulus-induced signal changes, and functional maps, while leaving stimulus-induced signal change amplitudes, image spatial resolution, and functional point-spread-function unaltered. We also provide supplementary data demonstrating that the method is equally applicable to supra-millimeter resolution 3- and 7-Tesla fMRI data, different cortical regions, stimulation/task paradigms, and acquisition strategies. The proposed denoising approach is expected to have a transformative impact on the scope and applications of fMRI to study the brain.
登录
查看更多内容
影响因子:
2.5
作者:
Bianciardi, Marta;Fukunaga, Masaki;van Gelderen, Peter;Horovitz, Silvina G.;de Zwart, Jacco A.;Shmueli, Karin;Duyn, Jeff H.
通讯作者:
Duyn, Jeff H.
DOI:
10.1073/pnas.89.12.5675
发表时间:
1992-06-15
影响因子:
11.1
作者:
KWONG, KK;BELLIVEAU, JW;ROSEN, BR
通讯作者:
ROSEN, BR
DOI:
10.1006/cbmr.1996.0014
发表时间:
1996-06-01
期刊:
COMPUTERS AND BIOMEDICAL RESEARCH
影响因子:
--
作者:
Cox, RW
通讯作者:
Cox, RW
影响因子:
3.3
作者:
Yaman B;Hosseini SAH;Moeller S;Ellermann J;Uğurbil K;Akçakaya M
通讯作者:
Akçakaya M
DOI:
10.1002/cmr.b.21268
发表时间:
2014-08
影响因子:
0.9
作者:
Vaidya, Manushka V.;Sodickson, Daniel K.;Lattanzi, Riccardo
通讯作者:
Lattanzi, Riccardo