Psychological stress-induced changes in salivary alpha-amylase and adrenergic activity
Psychological stress-induced changes in salivary alpha-amylase and adrenergic activity
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DOI：
10.1111/j.1442-2018.2010.00562.x
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发表时间：
2010-12-01
影响因子：
2.7
通讯作者：
Kang, Younhee
中科院分区：
文献类型：
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作者：
Kang, Younhee
本研究旨在探讨心理应激时唾液α-淀粉酶、血浆儿茶酚胺、血压和心率之间的关系。本研究采用前测-后测实验设计，并设对照组，采用重复测量。实验组（n = 16）接受大学学业期末考试作为心理压力，对照组（n = 17）不接受大学学业期末考试。唾液α-淀粉酶和血浆儿茶酚胺，血压和心率的水平进行了测量七次，压力和焦虑分别测量一次和两次，作为主观压力标志物。唾液α-淀粉酶水平的显着变化被发现在心理应激反应。然而，唾液α-淀粉酶与血浆儿茶酚胺、血压和心率的相关性仅部分具有统计学意义。总之，表明唾液α-淀粉酶在整个研究中对应激敏感。因此，唾液α-淀粉酶可用于在临床环境和护理研究中无创地测量压力，其中压力的影响可被仔细检查。此外，还可以探索压力引起的疾病的机制。
The aim of the study was to examine the relationships among salivary alpha-amylase, plasma catecholamines, blood pressure, and heart rate during psychological stress. This study used a pretest-post-test experimental design with a control group, using repeated measures. A total of 33 participants was divided into the experimental group (n = 16) that underwent a college academic final test as the psychological stress and the control group (n = 17) that did not undergo the test. The levels of salivary alpha-amylase and plasma catecholamines, blood pressure, and heart rate were measured seven times and stress and anxiety were measured once and twice, respectively, as subjective stress markers. Significant changes in the level of salivary alpha-amylase were found in response to psychological stress. However, the correlations of salivary alpha-amylase with the plasma catecholamines, blood pressure, and heart rate were only partially found to be statistically significant. In conclusion, it was shown that salivary alpha-amylase was sensitive to stress throughout this study. Thus, salivary alpha-amylase may be used to measure stress uninvasively in both clinical settings and nursing research where the effects of stress might be scrutinized. Furthermore, the mechanisms of illnesses that are induced by stress could be explored.