Multiplexed Bacterial Cell-Cell Communication via a Genetically Encoded CRISPRi-Based Multiplexer-Demultiplexer Circuit
Multiplexed Bacterial Cell-Cell Communication via a Genetically Encoded CRISPRi-Based Multiplexer-Demultiplexer Circuit
复制标题
通过基于 CRISPRi 的基因编码多路复用器-解复用器电路进行多路复用细菌细胞间通信
DOI:
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发表时间:
2016
期刊:
影响因子:
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通讯作者:
Jeffrey J. Tabor
中科院分区:
文献类型:
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作者:
John T. Sexton;Jeffrey J. Tabor
Living cells can be programmed with genetically encoded circuits to function as sophisticated decision-making devices, and communication among cells can facilitate increasingly complex, population-level computations. In this work, we describe a novel characterization platform for assessing the performance of genetically encoded circuits, and we demonstrate two genetically encoded combinational logic circuits, a multiplexer (MUX) and a demultiplexer (DEMUX), which can be combined to facilitate the communication of multiple independent signals between different strains of living bacterial cells.
影响因子:
4.7
作者:
Castillo-Hair SM;Sexton JT;Landry BP;Olson EJ;Igoshin OA;Tabor JJ
通讯作者:
Tabor JJ
影响因子:
4.7
作者:
Didovyk A;Borek B;Hasty J;Tsimring L
通讯作者:
Tsimring L