RNA-binding proteins as regulators of gene expression
RNA-binding proteins as regulators of gene expression
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DOI：
10.1016/s0959-437x(97)80148-7
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发表时间：
1997-06-01
影响因子：
4
通讯作者：
Dreyfuss, G
中科院分区：
文献类型：
--
作者：
Siomi, H;Dreyfuss, G
在真核生物遗传信息表达途径中，有许多转录后机制参与其中。这些过程由RNA上的顺式作用信号指定，并由特定的反式作用因子介导，包括RNA结合蛋白和小互补RNA。最近的信息已经开始定义RNA结合蛋白识别特定RNA序列并影响RNA分子的加工和功能的分子机制。
A plethora of post-transcriptional mechanisms are involved in essential steps in the pathway of genetic information expression in eukaryotes. These processes are specified by cis-acting signals on RNAs and are mediated by specific trans-acting factors, including RNA-binding proteins and small complementary RNAs. Recent information has begun to define the molecular mechanisms by which RNA-binding proteins recognize specific RNA sequences and influence the processing and function of RNA molecules.