A remarkably effective catalyst for the asymmetric transfer hydrogenation of aromatic ketones in water and air.
A remarkably effective catalyst for the asymmetric transfer hydrogenation of aromatic ketones in water and air.
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DOI：
10.1039/b507276j
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发表时间：
2005-08
影响因子：
4.9
通讯作者：
Xiaofeng Wu;D. Vinci;T. Ikariya;Jiangliang Xiao
中科院分区：
文献类型：
--
作者：
Xiaofeng Wu;D. Vinci;T. Ikariya;Jiangliang Xiao
[Cp*RhCl2]2与(1R，2R)-N-(p-toluenesulfonyl)-1，2-cyclohexanediamine原位生成的Rh(III)络合物是一种高效、坚固的催化剂，用于芳香酮在空气中HCOONa在水中的不对称转移氢化反应，可生成高达99%ee的醇。
A Rh(III) complex generated in situ from [Cp*RhCl2]2 and (1R,2R)-N-(p-toluenesulfonyl)-1,2-cyclohexanediamine (TsCYDN) serves as a remarkably effective, robust catalyst for the asymmetric transfer hydrogenation of aromatic ketones by HCOONa in water in air, affording alcohols in up to 99% ee.