SPIROCHETES ISOLATED FROM THE BLOOD OF 2 PATIENTS WITH LYME-DISEASE
SPIROCHETES ISOLATED FROM THE BLOOD OF 2 PATIENTS WITH LYME-DISEASE
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DOI：
10.1056/nejm198303313081302
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发表时间：
1983-01-01
影响因子：
158.5
通讯作者：
KASLOW, RA
中科院分区：
文献类型：
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作者：
BENACH, JL;BOSLER, EM;KASLOW, RA
从纽约[美国]长岛和韦斯特切斯特县的36例患者中的2例血液中分离出螺旋体，这些患者有提示莱姆病的体征和症状。螺旋体形态相似，血清学相同的生物体最近发现感染硬蜱dammini蜱，这是该地区特有的，并已被流行病学牵连莱姆病的载体。在这两个病人，有一个上升，在特定的抗螺旋体抗体配对标本的血清。因此，I.达米尼螺旋体在莱姆病中具有病原学作用。
Spirochetes were isolated from the blood of 2 of 36 patients in Long Island and Westchester County, New York [USA], who had signs and symptoms suggestive of Lyme disease. The spirochetes were morphologically similar and serologically identical to organisms recently found to infect Ixodes dammini ticks, which are endemic to the area and have been epidemiologically implicated as vectors of Lyme disease. In both patients, there was a rise in specific antispirochetal antibodies in paired specimens of serum. Thus, the I. dammini spirochete has an etiologic role in Lyme disease.