Short-term memory outcome measures: Psychometric evaluation and performance in youth with Down syndrome.
Short-term memory outcome measures: Psychometric evaluation and performance in youth with Down syndrome.
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DOI：
10.1016/j.ridd.2021.104147
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发表时间：
2022-01
影响因子：
3.1
通讯作者：
Esbensen AJ
中科院分区：
文献类型：
--
作者：
Schworer EK;Voth K;Hoffman EK;Esbensen AJ
改善唐氏综合症（DS）患者的短期记忆（STM）表现一直是最近临床试验的目标。 STM 结果测量的验证对于 DS 儿童和青少年试验的研究严谨性至关重要。目标。当前的研究调查了四种直接 STM 评估和一种日常记忆母体形式的心理测量特性。对 74 名患有 DS 的青少年样本进行了两次检查，相隔两周。还评估了总体认知能力。 OMQ-PF具有良好的可行性和分数分布，但直接测量的下限效应突出。所有测量的重测可靠性都很差到中等，并且 NEPSY-II 列表记忆和 DAS-II 物体回忆子测试的实践效果存在问题。观察到反应的共性，包括首要/近因效应，并且一些 STM 分数与整体认知能力相关。 OMQ-PF 满足大多数研究标准，但没有直接测量满足足够的标准，强烈推荐用于未来的临床试验。由于较高的认知能力与评估完成情况相关，因此 STM 测量可能需要进行调整，以便在更广泛的 DS 青少年各个认知能力水平的样本中使用。
Improving short-term memory (STM) performance for individuals with Down syndrome (DS) has been a target of recent clinical trials. Validation of STM outcome measures is essential for research rigor in trials among children and adolescents with DS. Aims. The current study investigated the psychometric properties of four direct STM assessments and one everyday memory parent form. Measures were administered to a sample of 74 youth with DS at two visits, two weeks apart. Overall cognitive abilities were also assessed. The OMQ-PF had good feasibility and distribution of scores, but floor effects were prominent for direct measures. Test-retest reliability was poor to moderate for all measures and practice effects were problematic for the NEPSY-II List Memory and DAS-II Recall of Objects subtests. Commonalities in responses were observed, including primacy/recency effects, and some STM scores were correlated with overall cognitive abilities. The OMQ-PF met most study criteria, but no direct measure met sufficient criteria to be strongly recommended for future clinical trials. Because higher cognitive abilities were related to assessment completion, STM measures may require adaptation for use in broader samples of youth with DS across all levels of cognitive ability.