Exercise in aging: its important role in mortality, obesity and insulin resistance.
Exercise in aging: its important role in mortality, obesity and insulin resistance.
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DOI：
10.2217/ahe.10.46
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发表时间：
2010-10
期刊：
影响因子：
--
通讯作者：
Ryan AS
中科院分区：
文献类型：
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作者：
Ryan AS
在过去几十年中，超重和肥胖的流行率急剧增加。肥胖和缺乏运动会增加患心血管疾病、2型糖尿病、高血压、血脂异常和某些癌症的风险。肥胖和身体健康水平低也与全因死亡率和心血管死亡率的风险增加有关。随着年龄的增长，中心性和总体肥胖，胰岛素抵抗和不活动增加。运动训练和增加健身促进身体成分的积极变化，提高胰岛素敏感性。本文将描述有氧运动和阻力运动训练对身体成分和肥胖的影响，并回顾研究运动训练对老年人葡萄糖代谢和胰岛素敏感性的影响。在超重和肥胖的胰岛素抵抗人群中，应强调采取积极的生活方式，以降低老年人群心血管事件的风险。
The prevalence of overweight and obesity has increased dramatically over the last several decades. Obesity and physical inactivity increase the risk for cardiovascular disease, Type 2 diabetes mellitus, hypertension, dyslipidemia and certain cancers. Obesity and low levels of physical fitness are also associated with increased risk of all-cause and cardiovascular mortality. Central and total obesity, insulin resistance and inactivity increase with age. Exercise training and increased fitness promote positive changes in body composition and improve insulin sensitivity. This article will describe the effects of exercise training, both aerobic and resistive, on body composition and obesity as well as review studies investigating the effects of exercise training on glucose metabolism and insulin sensitivity in older adults. Adopting a physically active lifestyle should be emphasized in overweight and obese individuals with insulin resistance to reduce the risk for cardiovascular events in the aging population.