New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.

New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.
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DOI:
10.1080/21541264.2017.1335269
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发表时间:
2018
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影响因子:
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通讯作者:
Vannini A
Vannini A
中科院分区:
其他
文献类型:
--
作者:
Gouge J;Vannini A

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在这里,我们讨论的作用Brf 2,RNA聚合酶III核心转录因子,作为一个主开关的氧化应激反应。我们强调了Brf 2与Nrf 2/Keap 1通路的相互作用,以及Brf 2在癌症和其他可能的调控中的作用。
Here, we discuss the role of Brf2, an RNA Polymerase III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.