Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress
Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress
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DOI：
10.1038/s41467-019-12045-4
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发表时间：
2019-09-05
影响因子：
16.6
通讯作者：
Voesenek, Laurentius A. C. J.
中科院分区：
文献类型：
--
作者：
Hartman, Sjon;Liu, Zeguang;Voesenek, Laurentius A. C. J.
及时感知不利的环境变化对生存至关重要。气体的动态变化是植物感知环境扰动（如淹没）的重要线索。在拟南芥中，氧和一氧化氮（NO）的变化控制ERFVII转录因子的稳定性。ERFVII蛋白水解受N-降解决定子途径调节，并介导对缺氧诱导的缺氧的适应。然而，植物如何检测和提前淹没信号仍然是一个谜。在这里，我们表明，植物可以迅速检测淹没通过被动乙烯截留，并使用此信号预适应即将到来的缺氧。乙烯可以通过增加NO清除剂PHYTOGLOBIN 1来增强缺氧前ERFVII的稳定性。这种乙烯介导的NO消耗和随后的ERFVII积累使植物适应随后的缺氧。我们的研究结果揭示了三种气体信号之间的生物联系，用于调节洪水生存，并确定了早期应激感知的关键调控目标，这可能是开发耐洪水作物的关键。
Timely perception of adverse environmental changes is critical for survival. Dynamic changes in gases are important cues for plants to sense environmental perturbations, such as submergence. In Arabidopsis thaliana, changes in oxygen and nitric oxide (NO) control the stability of ERFVII transcription factors. ERFVII proteolysis is regulated by the N-degron pathway and mediates adaptation to flooding-induced hypoxia. However, how plants detect and transduce early submergence signals remains elusive. Here we show that plants can rapidly detect submergence through passive ethylene entrapment and use this signal to pre-adapt to impending hypoxia. Ethylene can enhance ERFVII stability prior to hypoxia by increasing the NO-scavenger PHYTOGLOBIN1. This ethylene-mediated NO depletion and consequent ERFVII accumulation pre-adapts plants to survive subsequent hypoxia. Our results reveal the biological link between three gaseous signals for the regulation of flooding survival and identifies key regulatory targets for early stress perception that could be pivotal for developing flood-tolerant crops.