Premature deaths in schizophrenia and affective disorders. An analysis of survival curves and variables affecting the shortened survival.
Premature deaths in schizophrenia and affective disorders. An analysis of survival curves and variables affecting the shortened survival.
复制标题
精神分裂症和情感障碍的过早死亡。
DOI：
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发表时间：
1980
影响因子：
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通讯作者：
J. Fleming
中科院分区：
文献类型：
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作者：
M. Tsuang;R. Woolson;J. Fleming
通过与爱荷华州普通人群的比较，我们发现200名精神分裂症患者、100名躁狂症患者和225名抑郁症患者的生存期缩短。根据每个诊断组的生存曲线，按性别估计缩短的生存年数。影响缩短生存期的变量是诊断组、性别、入院时年龄和入院时的工资状况。其他死亡原因是自杀、事故、传染病和循环系统疾病。在我们的样本中，肿瘤死亡的绝对死亡率与爱荷华州的一般人群没有显著差异。然而，从同一数据得出的死亡率比例显示，精神分裂症和情感性精神障碍中因肿瘤而死亡的人数不足。需要进行精心设计的流行病学研究，以确定在主要精神病中是否存在癌症死亡的真实的缺陷。
We have found shortened survival in 200 schizophrenics, 100 manics, and 225 depressives by comparing them with the Iowa general population. The numbers of years of shortened survival were estimated from the survival curves of each diagnostic group by sex. Variables affecting shortened survival were diagnostic group, sex, age at admission, and pay status at admission. Excess causes of death were suicides, accidents, and infective and circulatory system diseases. The absolute mortality for deaths due to neoplasm in our sample was not significantly different than that in the Iowa general population. However, the proportional mortality from the same data showed a deficiency in deaths due to neoplasm in schizophrenia and affective disorders. Well-designed epidemiologic studies are needed to see if there is a real deficiency in deaths due to cancer in the major psychoses.