The Lund-Mackay staging system for chronic rhinosinusitis: How is it used and what does it predict?
The Lund-Mackay staging system for chronic rhinosinusitis: How is it used and what does it predict?
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DOI：
10.1016/j.otohns.2007.02.004
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发表时间：
2007-10-01
影响因子：
3.4
通讯作者：
Brown, Peter
中科院分区：
文献类型：
--
作者：
Hopkins, Claire;Browne, John P.;Brown, Peter
目的：Lund-Mackay评分广泛用于评估慢性鼻窦炎。我们的目的是描述其关系到其他措施的治疗前和治疗后的健康状况。研究设计：1840例慢性鼻窦炎在UK.RESULTS手术的患者进行多中心前瞻性研究：有没有绝对的手术阈值，但患者的Lund-Mackay评分较高进行了更广泛的手术。Lund-Mackay和SNOT-22评分之间没有相关性。Lund-Mackay随息肉病级别的增加而增加。Lund-Mackay评分与症状减轻（系数= 0.24，P = 0.02）、并发症发生率（比值比，1.08，95%CI 1.06至1.1）和翻修率（比值比，1.03，95%CI 1.001至1.06）相关。结论：Lund-Mackay评分衡量疾病与“主观”症状评分的不同方面。然而，它与疾病严重程度的其他标志物，手术的性质及其outcome.Significance相关：这表明了常用分期系统的优势和局限性。(c)2007年美国耳鼻咽喉头颈外科学会基金会。All rights reserved.
OBJECTIVES: The Lund-Mackay score is widely used in assessment of chronic rhinosinusitis. We aimed to describe its relationship to other measures of pre- and post-treatment health status.STUDY DESIGN: Multicenter prospective study of 1840 patients undergoing surgery for chronic rhinosinusitis in the UK.RESULTS: There was no absolute threshold for surgery, but patients with higher Lund-Mackay scores underwent more extensive surgery. There was no correlation between Lund-Mackay and SNOT-22 scores. The Lund-Mackay increased with increasing grade of polyposis. The Lund-Mackay score was associated with symptom reduction (coefficient = 0.24, P = 0.02) complication rates (odds ratio, 1.08, 95%CI 1.06 to 1.1), and revision rates (odds ratio, 1.03, 95% CI 1.001 to 1.06).CONCLUSIONS: The Lund-Mackay score measures a different aspect of disease to "subjective" symptom scores. However, it correlates Well with other markers of disease severity, the nature of surgery offered, and its outcome.SIGNIFICANCE: This demonstrates the strengths and limitations of a commonly used staging system. (c) 2007 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.