Development of paper-based microfluidic analytical device for iron assay using photomask printed with 3D printer for fabrication of hydrophilic and hydrophobic zones on paper by photolithography
Development of paper-based microfluidic analytical device for iron assay using photomask printed with 3D printer for fabrication of hydrophilic and hydrophobic zones on paper by photolithography
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DOI：
10.1016/j.aca.2015.04.014
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发表时间：
2015-07-09
影响因子：
6.2
通讯作者：
Shiraishi, Yukihide
中科院分区：
文献类型：
--
作者：
Asano, Hitoshi;Shiraishi, Yukihide
本文描述了一种用于铁分析的纸基微流控分析装置，该装置使用3D打印机打印的光掩模，通过光刻在纸上制造亲水区和疏水区。用于图案化纸基微流体分析装置的几种设计的光掩模可以用3D打印机容易地、快速地且廉价地打印。用十八烷基三氯硅烷正己烷溶液浸渍色谱纸并疏水化。在纸的疏水区通过光掩模暴露于UV光之后，产生亲水区。最小的功能性亲水通道和疏水屏障约为1.5 μ m。500亩米和约。100 μ m宽。该方法对亲水通道和疏水屏障具有高稳定性、高分辨率和高精度。将该试纸应用于邻二氮杂菲比色法分析水样中的铁。(C)2015 Elsevier B.V.版权所有。
This paper describes a paper-based microfluidic analytical device for iron assay using a photomask printed with a 3D printer for fabrication of hydrophilic and hydrophobic zones on the paper by photolithography. Several designed photomasks for patterning paper-based microfluidic analytical devices can be printed with a 3D printer easily, rapidly and inexpensively. A chromatography paper was impregnated with the octadecyltrichlorosilane n-hexane solution and hydrophobized. After the hydrophobic zone of the paper was exposed to the UV light through the photomask, the hydrophilic zone was generated. The smallest functional hydrophilic channel and hydrophobic barrier were ca. 500 mu m and ca. 100 mu m in width, respectively. The fabrication method has high stability, resolution and precision for hydrophilic channel and hydrophobic barrier. This test paper was applied to the analysis of iron in water samples using a colorimetry with phenanthroline. (C) 2015 Elsevier B.V. All rights reserved.