PRACTICAL APPLICATIONS OF CHEMICAL-SHIFT IMAGING
PRACTICAL APPLICATIONS OF CHEMICAL-SHIFT IMAGING
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DOI：
10.1002/nbm.1940050508
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发表时间：
1992-09-01
影响因子：
2.9
通讯作者：
BROWN, TR
中科院分区：
文献类型：
--
作者：
BROWN, TR
简要回顾了频谱定位的方法，并将其分为两类：使用相位编码的方法和使用恒定梯度中的频率选择性RF脉冲的方法。在后一种情况下，一个潜在的令人不安的人为因素是不同化合物的空间配准不良，这会导致较小区域的P-31光谱出现严重错误。化学位移成像（CSI）是相位编码技术的一个典型例子。导出了观测信号与真实信号（点扩散函数）关系的解析表达式。CSI在一个，两个和三个维度的例子被用来说明这种类型的本地化的原则。
Methods of spectral localization are briefly reviewed and divided into two classes: those using phase encoding and those using frequency selective RF pulses in a constant gradient. A potentially troubling artifact in the latter case is the spatial misregistration of different compounds which causes serious errors in P-31 spectra from smaller regions. Chemical shift imaging (CSI) is presented as a typical example of phase encoding techniques. An analytical expression for the relationship of the signal observed to the true signal (the point spread function) is derived. Examples of CSI in one, two, and three dimensions are used to illustrate the principles of this type of localization.