Structural studies of {6Li} 2-lithiopyrrolidines using NMR spectroscopy
Structural studies of {6Li} 2-lithiopyrrolidines using NMR spectroscopy
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DOI：
10.1016/j.tet.2005.01.098
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发表时间：
2005-03-28
期刊：
影响因子：
2.1
通讯作者：
Coldham, I
中科院分区：
文献类型：
--
作者：
Gawley, RE;Klein, R;Coldham, I
制备了一系列n -取代的2-锂吡咯烷类化合物，并用Li-6和C-13 NMR对其结构进行了表征。根据吡咯烷环上n取代基和取代基的性质，提出了聚集和动态溶剂化效应的证据。对N-Boc（配位羰基）、n -甲氧基乙基（配位甲氧基）和n -烷基（无配位基）杂环进行了研究，以代表三种不同类型的有机锂：偶极稳定、不稳定和螯合、不稳定。(c) 2005 Elsevier Ltd版权所有。
A selection of N-substituted 2-lithiopyrrolidines were prepared and their structures were investigated by Li-6 and C-13 NMR spectroscopy. Evidence is presented for aggregation and dynamic solvation effects, depending on the nature of the N-substituent and substituents on the pyrrolidine ring. Studies were performed with N-Boc (coordinating carbonyl group), N-methoxyethyl (coordinating methoxy group) and N-alkyl (no coordinating group) heterocycles to represent three different classes of organolithiums: dipole-stabilized, unstabilized and chelated, and unstabilized. (c) 2005 Elsevier Ltd. All rights reserved.