Trunk muscle strength is a strong predictor of bone loss in postmenopausal women
Trunk muscle strength is a strong predictor of bone loss in postmenopausal women
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DOI：
10.1097/01.blo.0000200232.91913.74
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发表时间：
2006-02-01
影响因子：
4.2
通讯作者：
Kusaka, Yukinori
中科院分区：
文献类型：
--
作者：
Iki, Masayuki;Saito, Yukie;Kusaka, Yukinori
为了澄清躯干肌肉力量和自我报告的运动习惯是否能预测健康绝经后妇女随后的骨质流失，我们调查了143名社区居住的绝经后日本妇女（年龄：59.9±6.5岁），基线时没有任何影响骨代谢的疾病，并对143名受试者中的109名进行了4年的随访。基线和随访时脊柱骨密度用DEXA测量，以确定随访期间骨密度的年变化。骨密度年损失率超过-1.78%（比平均损失率低1个标准差）的受试者被定义为快速骨质流失。在基线时测量躯干屈肌和伸肌的等速同心和偏心峰值扭矩。通过详细访谈对被试的运动习惯进行评估。研究发现，躯干偏侧屈肌和伸肌扭矩与骨密度变化呈剂量依赖性正相关，而运动习惯没有相关性。伸肌扭矩较低的组与较高的组相比，出现快速骨质流失的风险高10倍。绝经后的妇女躯干肌转矩减少，骨质疏松的风险可能增加，应作为预防措施的目标群体。
To clarify whether trunk muscle strength and self-reported exercise habits predict subsequent bone loss in healthy postmenopausal women, we examined 143 community-dwelling ambulatory postmenopausal Japanese women (age: 59.9 +/- 6.5 years) without any diseases affecting bone metabolism at baseline, and followed 109 of the 143 subjects for 4 years. Bone mineral density at baseline and at followup was measured at the spine by DEXA to determine the annual change in bone mineral density during the followup. Subjects who lost bone mineral density at an annual rate exceeding -1.78% (1 standard deviation below the mean rate) were defined as rapid bone losers. The isokinetic concentric and eccentric peak torques of the trunk flexors and extensors were measured at baseline. The exercise habits of the subjects were evaluated through detailed interviews. The eccentric trunk flexor and extensor torques were found to correlate with a positive dose-dependent effect on change in bone mineral density while exercise habits showed no correlation. The lower tertile group for the extensor torque showed a ten-fold greater risk for rapid bone loss compared with the upper tertile group. Postmenopausal women with decreased trunk muscle torque may be at increased risk for osteoporosis and should be a target group for preventive measures.