A comprehensive metabolic profiling of the metabolically healthy obesity phenotype
A comprehensive metabolic profiling of the metabolically healthy obesity phenotype
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DOI：
10.1186/s12944-020-01273-z
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发表时间：
2020-05-09
影响因子：
4.5
通讯作者：
Ulven, Stine M.
中科院分区：
文献类型：
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作者：
Telle-Hansen, Vibeke H.;Christensen, Jacob J.;Ulven, Stine M.
背景 肥胖患病率的不断增加构成了世界范围内的一个主要健康问题。肥胖个体的一个亚群被描述为“代谢健康肥胖”（MHO）。与代谢不健康肥胖 (MUO) 相比，MHO 表型具有有利的风险特征。尽管如此，就全面风险评估而言，MHO 表型的特征仍然欠佳。我们的目的是增加对与健康和不健康肥胖相关的代谢变化的了解。方法 在这项横断面研究中，肥胖（体重指数 (BMI) >= 30 kg/m(2)）或体重正常 (NW) (BMI) 的男性和女性（18-70 岁）
Background The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as "metabolically healthy obese" (MHO). In contrast to metabolically unhealthy obese (MUO), the MHO phenotype has a favorable risk profile. Despite this, the MHO phenotype is still sub-optimally characterized with respect to a comprehensive risk assessment. Our aim was to increase the understanding of metabolic alterations associated with healthy and unhealthy obesity. Methods In this cross-sectional study, men and women (18-70 years) with obesity (body mass index (BMI) >= 30 kg/m(2)) or normal weight (NW) (BMI