Clinical Stratification of Pediatric Patients with Idiopathic Thoracic Aortic Aneurysm
Clinical Stratification of Pediatric Patients with Idiopathic Thoracic Aortic Aneurysm
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DOI：
10.1016/j.jpeds.2015.02.042
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发表时间：
2015-07-01
影响因子：
5.1
通讯作者：
Hinton, Robert B.
中科院分区：
文献类型：
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作者：
Landis, Benjamin J.;Ware, Stephanie M.;Hinton, Robert B.
目的描述未被临床诊断为马凡综合征（MFS）或相关结缔组织疾病的胸主动脉瘤（TAA）患儿的总体表型。我们假设非心血管异常的存在与TAA的严重程度相关，并且药物治疗可以减少TAA的进展。研究设计这是一个回顾性病例系列，研究对象是年龄在18岁至18岁之间的TAA患者。
Objectives To describe the global phenotypes of pediatric patients with thoracic aortic aneurysm (TAA) who do not have a clinical diagnosis of Marfan syndrome (MFS) or related connective tissue disorders. We hypothesized that the presence of noncardiovascular abnormalities correlate with TAA severity and that medical therapy reduces TAA progression.Study design This is a retrospective case series of patients with TAA age