Erratum: Type 2 Autoimmune Pancreatitis (Idiopathic Duct-Centric Pancreatitis) Highlighting Patients Presenting as Clinical Acute Pancreatitis: A Single-Center Experience
Erratum: Type 2 Autoimmune Pancreatitis (Idiopathic Duct-Centric Pancreatitis) Highlighting Patients Presenting as Clinical Acute Pancreatitis: A Single-Center Experience
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DOI：
10.5009/gnl13051
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发表时间：
2019-04
期刊：
影响因子：
3.4
通讯作者：
D. Oh;T. Song;Sung-Hoon Moon;J. Kim;Joo Nam Lee;Seung‐Mo Hong;Joune Seup Lee;S. Jo;D. Cho;D. Park;S. Lee;D. Seo;S. Lee;Myung-Hwan Kim
中科院分区：
文献类型：
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作者：
D. Oh;T. Song;Sung-Hoon Moon;J. Kim;Joo Nam Lee;Seung‐Mo Hong;Joune Seup Lee;S. Jo;D. Cho;D. Park;S. Lee;D. Seo;S. Lee;Myung-Hwan Kim
背景/目的2型自身免疫性胰腺炎（AIP）在东亚被认为是极其罕见的。本研究旨在阐明2型AIP的患病率、临床特征和影像学表现，强调在单中心以急性胰腺炎表现的患者。方法根据国际公认诊断标准对2型AIP进行分型。比较以急性胰腺炎和胆源性胰腺炎为表现的2型AIP的影像学表现。结果244例AIP患者中，2型AIP 27例（11.1%），其中明确诊断15例（55.5%），可能诊断12例（44.5%）。2型AIP患者的中位年龄为29岁（四分位距，20至39岁）。急性胰腺炎是最常见的初始表现（n=17，63%），而梗阻性黄疸，目前只有一个病人。44.4%（12/27）的患者溃疡性结肠炎（UC）与2型AIP相关。胰腺影像学表现如胰腺弥漫性肿大延迟强化、局灶性肿大或肿块均匀强化、胰周脂肪浸润或积液不存在或极轻微、多灶性主胰管扩张等有助于鉴别2型AIP与胆源性胰腺炎。在随访期间（中位数，32.3个月），2例患者（2/25，8%）出现复发。结论在韩国，2型AIP并不像以前认为的那样罕见。总体而言，2型AIP的临床特征与西方国家相似。2型AIP应考虑在年轻UC患者的急性胰腺炎的病因不明。
Background/aims Type 2 autoimmune pancreatitis (AIP) has been considered extremely rare in East Asia. This study aimed to clarify the prevalence, clinical characteristics and radiological findings of type 2 AIP highlighting patients presenting as acute pancreatitis in a single center. Methods Type 2 AIP patients were classified according to International Consensus Diagnostic Criteria. Radiological findings were compared between type 2 AIP presenting as acute pancreatitis and gallstone pancreatitis. Results Among 244 patients with AIP, 27 (11.1%) had type 2 AIP (definite, 15 [55.5%] and probable 12 [44.5%]). The median age of patients with type 2 AIP was 29 years (interquartile range, 20 to 39 years). Acute pancreatitis was the most common initial presentation (n=17, 63%) while obstructive jaundice was present in only one patient. Ulcerative colitis (UC) was associated with type 2 AIP in 44.4% (12/27) of patients. Radiological pancreatic imaging such as delayed enhancement of diffusely enlarged pancreas, homogeneous enhancement of focal enlargement/mass, absent/minimal peripancreatic fat infiltration or fluid collection, and multifocal main pancreatic duct narrowings were helpful for differentiating type 2 AIP from gallstone pancreatitis. During follow-up (median, 32.3 months), two patients (2/25, 8%) experienced relapse. Conclusions In South Korea, type 2 AIP is not as rare as previously thought. Overall, the clinical profile of type 2 AIP was similar to that of Western countries. Type 2 AIP should be considered in young UC patients with acute pancreatitis of uncertain etiology.