Nucleotide sequence of the dextran glucosidase (dexB) gene of Streptococcus mutans.
Nucleotide sequence of the dextran glucosidase (dexB) gene of Streptococcus mutans.
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DOI：
10.1099/00221287-136-5-803
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发表时间：
1990-05
期刊：
影响因子：
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通讯作者：
R. Russell;J. Ferretti
中科院分区：
文献类型：
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作者：
R. Russell;J. Ferretti
在变形链球菌染色体上与先前表征的gtfA基因相邻的区域中的DNA的核苷酸测序揭示了两个长开放阅读框的存在。其中之一对应于dexB基因，并已显示编码细胞内外葡聚糖酶（葡聚糖葡糖苷酶），其具有短的异麦芽糖醇作为优选底物。与其他已发表序列的比较表明，dexB基因产物与来自各种来源的酶具有相似性区域，这些酶攻击其他葡萄糖聚合物。
Nucleotide sequencing of DNA in the region of the Streptococcus mutans chromosome adjacent to the previously characterized gtfA gene revealed the presence of two long open reading frames. One of these corresponds to the dexB gene and has been shown to encode an intracellular exodextranase (dextran glucosidase) which has short isomaltosaccharides as preferred substrates. Comparison with other published sequences showed that the dexB gene product shares regions of similarity with enzymes, from a variety of sources, which attack other glucose polymers.