Reducing noninfectious risks of blood transfusion.

Reducing noninfectious risks of blood transfusion.
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DOI:
10.1097/aln.0b013e31822a22d9
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发表时间:
2011-09
期刊:
影响因子:
8.8
通讯作者:
Gropper MA
Gropper MA
中科院分区:
医学1区
文献类型:
--
作者:
Gilliss BM;Looney MR;Gropper MA

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As screening for transfusion-associated infections has improved, non-infectious complications of transfusion now cause the majority of morbidity and mortality associated with transfusion in the United States. For example, transfusion-related acute lung injury, transfusion-associated circulatory overload, and hemolytic transfusion-reactions are the first, second, and third leading causes of death from transfusion respectively. These complications and others are reviewed here and several controversial methods for prevention of non-infectious complications of transfusion are discussed; universal leukoreduction of red cell units, use of male-only plasma, and restriction of red cell storage age.