Evaluation of the Appropriateness of the Japanese Metabolic Syndrome Diagnostic Criteria on Routine Medical Health Checkups in a Rural Area.
Evaluation of the Appropriateness of the Japanese Metabolic Syndrome Diagnostic Criteria on Routine Medical Health Checkups in a Rural Area.
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日本代谢综合征诊断标准对农村地区常规健康检查的适宜性评价。
DOI：
10.2185/jrm.1.2_30
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
H. Yamase
中科院分区：
文献类型：
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作者：
H. Ohbayashi;T. Naruse;Masaki Yamada;Koutaro Hayashi;Sirou Kawashima;Hiroyuki Nosaka;H. Yamase
目的：日本于2005年4月公布了代谢综合征（MetS）的诊断标准。然而，还没有在农村地区进行大规模的研究来确认这些标准。我们研究了在我们位于农村地区的医院接受常规医疗健康检查的受试者中MetS的患病率。这些数据被用来调查MetS诊断标准的适当性。对象和方法：回顾性检查2340例受试者的MetS状态2004年4月至2005年3月在我院进行常规体检的男性1408例，女性932例，平均年龄49.6 ± 9.7岁。在1408名男性和932名女性中，209名男性（14.8%）和23名女性（2.5%）被诊断为MetS。44名男性（3.1%）和4名女性（0.4%）符合代谢紊乱的所有三项诊断标准。在女性组中，932名女性中只有8.7%符合腰围≥90 cm的标准。因为这个腰围标准在第一次筛选时使用，但大多数妇女不符合，所以将她们从我们的研究中排除。采用受试者工作特征（ROC）分析，男性腰围的临界值为85.0 cm（敏感性0.750，特异性0.564），女性腰围的临界值为79.5 cm（敏感性0.787，特异性0.709）。如果将女性腰围标准设定为≥ 79.5cm，则符合标准的女性为48例（5.2%）。结论：从预防医学的角度来看，日本男性MetS诊断标准是相当合适的。然而，对于女性，腰围≥90 cm的标准设定过高，大多数女性受试者均未达到。因此，日本女性MetS标准，特别是腰围的临界值，需要进一步验证。
Objective: The diagnostic criteria for the metabolic syndrome (MetS) were published in Japan in April 2005. However, there have been no large-scale studies in rural areas to confirm these criteria. We examined the prevalence of MetS in subjects who had undergone a routine medical health checkup at our hospital, located in a rural area. This data was used to investigate the appropriateness of the diagnostic criteria for MetS.Subjects and Methods: The MetS status was examined retrospectively in 2340 subjects (1408 men, 932 women ; mean age 49.6 ± 9.7 years) who underwent a routine medical health checkup at our hospital between April 2004 and March 2005.Results: Of the 1408 men and 932 women, 209 men (14.8%) and 23 women (2.5%) were diagnosed with MetS. Forty-four men (3.1%) and 4 women (0.4%) met all three diagnostic criteria for metabolic disorders. In the female group, only 8.7% of the 932 women met the waist circumference criterion of ≥90 cm. Because this waist circumference criterion was used during the first screening but was not met by most of the women, they were eliminated from our study. Using receiver operating characteristic (ROC) analysis, the cutoff values for waist circumference were 85.0 cm (sensitivity 0.750, specificity 0.564) in men and 79.5 cm (sensitivity 0.787, specificity 0.709) in women. If the women's waist circumference criterion had been set at the value of ≥79.5 cm, this would have resulted in 48 (5.2%) women meeting the criterion.Conclusion: From the viewpoint of preventive medicine, the Japanese male MetS diagnostic criteria are fairly appropriate. However, for the women, the waist circumference criterion of ≥90 cm has been set too high and was not met by most of the female subjects. Therefore, the Japanese MetS criteria for women, particularly the cutoff value for waist circumference, requires further verification.